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PT-141, 10mg/Oxytocin, 5mg Nasal

PT-141, 10mg/Oxytocin, 5mg Nasal

Regular price $292.00 USD
Regular price Sale price $292.00 USD
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❇️ Product Specifications (Read More)

Category Sexual Health Research — Dual Peptide
Form Nasal spray — combination formula
PT-141 content 10 mg (Bremelanotide)
Oxytocin content 5 mg
Mechanism (PT-141) MC3R/MC4R central arousal activation
Mechanism (Oxytocin) OTR-mediated bonding, trust, social reward
Purity ≥99% each peptide (HPLC verified)

PT-141 + Oxytocin Nasal Spray is a dual-peptide combination delivering Bremelanotide's central arousal activation alongside Oxytocin's bonding and social reward pathways — two complementary CNS mechanisms in a single nasal administration. This combination is studied for research into the neurochemical overlap between physical desire and emotional intimacy.

Why PT-141 + Oxytocin Together?

  • Dual CNS mechanism: PT-141 activates melanocortin receptors (MC3R/MC4R) for arousal; Oxytocin activates oxytocin receptors (OTR) for bonding, trust, and social reward — two independent but neurobiologically complementary pathways
  • Addressing arousal + intimacy simultaneously: Sexual desire (PT-141 mechanism) and emotional connection (Oxytocin mechanism) involve distinct but overlapping neural circuits. Research interest focuses on whether combined activation amplifies behavioural outcomes beyond either peptide alone
  • Nasal delivery for both peptides: Intranasal Oxytocin is the most studied delivery route for this peptide — direct access to the brain via olfactory/trigeminal pathways. Combining with intranasal PT-141 in one formulation provides dual CNS delivery with a single administration
  • HSDD and relationship research: Relevant for studying complex sexual dysfunction models where desire, arousal, and emotional intimacy components are all contributing factors

Research Dosing Protocol

Administer intranasally 15–45 minutes before the observation window. The Oxytocin component requires intranasal delivery for optimal CNS access. PT-141 onset: 10–30 minutes. Oxytocin onset (CNS effects): 15–45 minutes. Store refrigerated.

Mechanism of Action

PT-141: Activates MC3R/MC4R in the hypothalamus, modulating dopaminergic and serotonergic pathways governing sexual desire and arousal, independently of the vascular system.

Oxytocin: Binds oxytocin receptors (OTR) in the amygdala, nucleus accumbens, and prefrontal cortex, modulating trust, social bonding, reward processing, and emotional attunement during social interactions.

Key Research Areas

  • Multi-component sexual dysfunction models (desire + intimacy)
  • Neurobiological overlap between arousal (MC pathway) and bonding (OTR pathway)
  • HSDD with relational/emotional component
  • Intranasal peptide CNS delivery studies
  • Oxytocin + melanocortin pathway interaction research

Quality Assurance

All Core Sup products are sourced from cGMP-compliant, FDA-registered facilities and independently tested for identity (mass spectrometry), purity (≥99% HPLC), and concentration accuracy. Certificate of Analysis available on request — email info@coresup.shop with product name and batch number.

Important Notice

This product is supplied for research and educational purposes only. Not for human consumption or therapeutic use. Always consult a qualified UAE-licensed healthcare professional. Core Sup operates in compliance with UAE MOHAP and EDE regulations.

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PT-141, 10mg/Oxytocin, 5mg Nasal | Buy in Dubai & UAE | Core Sup

PT-141, 10mg/Oxytocin, 5mg Nasal (Bremelanotide) is a synthetic melanocortin receptor agonist developed from the melanocyte-stimulating hormone (MSH). Unlike conventional sexual enhancement drugs that work through the vascular system, PT-141 works directly through the central nervous system — activating melanocortin receptors in the brain to enhance sexual desire, arousal, and performance in both men and women.

PT-141 10mg is FDA-approved under the brand name Vyleesi for hypoactive sexual desire disorder (HSDD) in pre-menopausal women, and is widely used off-label for sexual enhancement in men. Clinical studies demonstrate improved libido, stronger and more frequent arousal, enhanced sexual satisfaction, and increased confidence. Effects typically begin within 30-60 minutes and can last 6-12 hours. It has shown effectiveness even in patients who do not respond to PDE5 inhibitors.

Core Sup provides PT-141 10mg in injectable and nasal spray formats for convenient administration. All products are sourced from certified research-grade laboratories with verified purity. Discreet, confidential packaging and fast delivery across Dubai, Abu Dhabi, and all UAE emirates. Available as a standalone product or in combination blends with Oxytocin for enhanced sexual wellness protocols.