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| Category | Cognitive |
|---|---|
| Tags | Nootropic, Neuroprotective |
| Half-life | 30 min |
| Elimination time | 2.5 hours |
Semax is a synthetic peptide analog of ACTH (4-10) developed in Russia. It is approved in Russia and Ukraine as a nasal spray for neurological conditions.
100-600 mcg intranasally, 1-3 times daily.
Generally well-tolerated. Approved medication in Russia. May cause irritability at high doses. Not FDA-approved in the US.
Semax upregulates BDNF (brain-derived neurotrophic factor) and modulates dopamine and serotonin systems. As an ACTH analog, it provides neuroprotective effects without adrenal stimulation at standard doses.
Semax is a heptapeptide derived from ACTH (Adrenocorticotropic Hormone) that lacks hormonal activity but possesses potent nootropic and neuroprotective properties. It increases levels of Brain-Derived Neurotrophic Factor (BDNF) and NGF, supporting neuron survival and plasticity. Adamax is a potent derivative (N-acetyl Semax + adamantane group) that is more stable and lipophilic, crossing the blood-brain barrier more effectively.
Clinical indications include stroke recovery, optic nerve disease, cognitive decline, and ADHD. It improves focus, memory consolidation, and mental clarity without the jitteriness of stimulants. It also has stress-protective and mood-stabilizing effects.
Dosage ranges from 200 mcg to 1 mg daily, typically administered intranasally. For Adamax, lower doses (e.g., 200-500 mcg) are effective due to higher potency. It is often cycled or used as needed for intense mental work.
All Core Sup products are sourced from cGMP-compliant, FDA-registered facilities and undergo independent third-party laboratory testing for identity, purity, and concentration accuracy. Certificate of Analysis (CoA) available on request.
This product is supplied for research and educational purposes only. It is not intended for human consumption, diagnosis, treatment, or prevention of any medical condition. Always consult a qualified healthcare professional before use. Core Sup operates in compliance with UAE MOHAP regulations.
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